Error 500. CRM not working

Good day! The second day CRM box.trudovik.com.ua does not work, constantly gives error 500. If you constantly reload the page in the browser, sometimes CRM starts, but after a couple of transitions on the items, again gives error 500. In the "Server Load Control Panel" shows a very strange graph. There is space on the disk, but this morning in the browser there was such an error Uncaught ConnectionManager_Exception: Cannot connect to database: Too many connections in /var/www/boxtrudovikcomu/web1/web/packages/ConnectionManager/ConnectionManager_MySQLi.class.php:49 You may have run out of disk space.